The easiest way to give your pet a pill is to hide it in a small amount of a favorite food, such as canned pet food, peanut butter, soft cheese, or tuna. Watch carefully to be sure your pet does not spit out the pill while managing to eat the treat!
What if my pet won’t eat the treat or keeps spitting out the pill?
In this case, you will need to administer it directly into your pet’s mouth. Ask your vet for a demonstration and advice on the proper technique.
How can I control my pet while administering a pill?
It is a good idea to have one person hold the pet while a second administers the pill. It is often easiest to place a cat or small dog in your lap, possibly wrapping a cat in a towel with only its head exposed. Larger dogs can be backed into a corner or placed on a metal or tile surface where they have less traction and you have more control.
***Adapted from: http://www.webvet.com